Brain and spinal cord MRI are recognised as the most important paraclinical tools for the diagnosis of MS. However, the role of MR imaging in Multiple Sclerosis (MS) goes far beyond the diagnostic process and differential diagnosis. MR imaging can also provide useful prognostic information in terms of long term disability prediction. Moreover, with the introduction of the new generation of immunomodulatory drugs for the treatment of MS, MRI also plays an important role in treatment monitoring. This includes the prediction of treatment response, the assessment of treatment efficacy and treatment safety. This course will present an update on the diagnosis and differential diagnosis of MS and other demyelinating diseases, in the application of diagnostic criteria of MS, and on the value of MRI for monitoring and predicting treatment response. All this information should help radiologists in the standardisation and optimisation of the use of MR imaging in the management of MS in clinical practice.

• To be aware of the clinical importance of an early and accurate diagnosis in MS, and the role of MRI for that purpose • To be familiar with the typical/atypical MRI features of brain and spinal cord MS lesions • To review the current diagnostic criteria for MS • To understand the role of MRI in the therapeutic management of MS

Residents on year 4 and General radiologists