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0.5 CME Credits

Advanced MRI: Perfusion

DSC and ASL perfusion MRI are examined through technique, interpretation, pitfalls, and neuro-oncological and vascular applications.
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Description

Dynamic susceptibility contrast acquisition, signal-time curves, cerebral blood volume calculation, and leakage effects establish the technical basis. Perfusion is applied to tumour diagnosis and grading, glioma transformation, and treatment effect versus recurrence before arterial spin labelling is introduced for perfusion, shunts, and stenosis.

Learning Objectives

  • Perform and interpret DSC perfusion using signal-time curves and cerebral blood volume maps.
  • Recognise leakage and other pitfalls that affect perfusion measurements.
  • Apply DSC and ASL findings to brain tumours, treatment response, and neurovascular disease.
  • Use arterial spin labelling to assess perfusion abnormalities, shunts, and vascular stenosis.

Topics Covered

To jump to a specific chapter, click on the chapter title once the video is playing.
00:07 - Introduction to MR Perfusion and Lecture Overview
00:36 - Brain Tumors: Understanding Perfusion and Case Studies
00:58 - Dynamic Susceptibility Contrast-Enhanced MR Perfusion
03:38 - Technique and Steps for DSC MR Perfusion
05:33 - Understanding Signal Time Curve in Perfusion Imaging
07:37 - Calculating and Interpreting Cerebral Blood Volume (CBV)
10:29 - Pitfalls in Perfusion Studies: Leakage Effects
13:04 - Tips for Performing DSC Perfusion
15:09 - Applications of Perfusion: Tumor Grading and Diagnosis
17:28 - Monitoring Glioma Transformation with Perfusion
22:44 - Differentiating Treatment Effects from Tumor Recurrence
28:57 - Using Perfusion in Diagnosis of Neurological Conditions
36:33 - Advanced Applications and Report Recommendations
32:41 - Introduction to ASL for Perfusion in Neurovascular Diseases
39:39 - Identifying Shunts and Stenosis Using ASL
42:52 - Final Thoughts and Conclusion